🧬 Entropion in Maine Coon Cats — Let’s Talk Honestly
- Svetlana Jacobson
- Apr 8
- 3 min read

Veterinary ophthalmology experts note that entropion is commonly seen in Maine Coons. But the exact mode of inheritance in this breed is not understood, but a familial predisposition is suspected.
In other words: everyone is guessing — no one truly knows.
But when something happens, the breeder is usually blamed.
I don’t like surprises. I’ve spent years learning how to raise healthy animals — and now I teach others to do the same. So I decided to look into entropion seriously, and understand what’s really going on.
Let’s clarify:
Is this a genetic disease? A predisposition? Or something else entirely?
📖 Terminology: Genetic Disease vs. Hereditary Predisposition
These are not the same thing, and confusing them is a mistake.
1. Genetic Disease
A genetic disease has a clearly identified cause: a specific gene mutation.
✅ Features:
• There is a DNA test that confirms it
• It follows a known inheritance pattern (dominant or recessive)
• It can be proven to pass from parents to offspring
• A responsible breeder can test for it and eliminate it from their lines
Examples:
• HCM (Hypertrophic Cardiomyopathy – MYBPC3 gene)
• SMA (Spinal Muscular Atrophy)
• PKDef (Pyruvate Kinase Deficiency)
There are 49 known genetic diseases in standard feline testing panels.
🧬 I test my breeding cats for all of them. But entropion is not one of them.
2. Hereditary Predisposition
This is a completely different concept. It’s not a disease, but a tendency.
📌 It means:
• A condition is seen more often in a breed or line
• But the exact gene is unknown
• There is no test
• Inheritance is not understood
• Physical traits like skull shape, hormones, or skin tension might play a role — but there is no proof
🔎 This is exactly the case with entropion.
🧠 What do the veterinary authorities say?
According to:
• Merck Veterinary Manual
• Cornell Feline Health Center
• American College of Veterinary Ophthalmologists (ACVO)
“Entropion in cats can be primary (developmental) or secondary to trauma, inflammation, or infection. The genetic basis in cats is unconfirmed.”
📌 In simple terms: – Yes, it appears more often in Maine Coons
– Yes, there is a suspected link to breed type
– But:
→ There is no test
→ The inheritance mechanism is not known
→ It can also be acquired from other causes
⚠️ Common Causes of Entropion:
🔹 Eye inflammation or infection
– Especially in kittens, where tissue is still developing
– This can cause the eyelid to contract inward temporarily
🔹 Trauma
– A fall, scratch, rough handling, stress
– Especially in young cats with soft tissue
🔹 Vitamin and mineral deficiency, especially:
– Taurine (for muscles and eyes)
– Vitamins A, E, B-complex
– Zinc, copper, calcium
🔹 Anatomical structure
– Large jowls in intact males
– Heavy skin folds
– Deep-set eyes or broad skull structure
🧩 The Truth:
Entropion can develop from multiple factors.
No one can definitively say whether it is hereditary or not.
If it were a clearly genetic disease: – There would be a DNA test
– It would be regulated in breeding
– The inheritance would be clearly defined
But none of that exists.
So — blaming the breeder has no scientific basis.
🧑⚕️ What is a breeder actually responsible for?
✅ A responsible breeder should:
– Use only healthy animals in breeding
– Never include in a breeding program any animal that has undergone surgery for entropion
– Monitor offspring health
– Be open and honest with buyers
❌ But no breeder can be held responsible for:
– A condition that has no test
– No proven pattern
– And that may be caused by external factors in the new home
📌 Final Conclusion
There is no valid reason to accuse the breeder of causing entropion.
– It is not a genetically confirmed disease
– There is no test
– There is no scientific consensus
– Many other causes are possible
– It is more fair — and more accurate — to accept that entropion in Maine Coons is a risk that comes with the breed, not a failure of the breeder.
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